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Fig. 2 | Applied Cancer Research

Fig. 2

From: RUNX2 and WWOX genes as molecular biomarkers and candidates for targeted therapy in Egyptian patients with primary conventional osteosarcoma

Fig. 2

Cases of osteosarcoma showing a negative immunostaining of RUNX2 in normal bony tissue (X400), b a case of OS, grade 2 showing moderate nuclear immunostaining of RUNX2 (X200), c a case of OS, grade 3 showing marked and diffuse nuclear immunostaining of RUNX2 (X400), d Bar chart showing the frequency of RUNX2 protein expression in OS cases according to groups, e Amplification plots of RUNX2, SYBR green, MAX3000P (Applied Biosystems, Inc., Foster City, CA, USA), and f Box blot graph showing increased RUNX2 gene and protein expressions in OS cases

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