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Table 3 Results of immunostaining quantitatively analyzed using an automated imaging system (ACIS III)

From: Profile of apoptotic proteins in oral squamous cell carcinoma: A cluster analysis of 171 cases

Protein

Intensity (range)

Median value of intensity

Intensity (range)

Median value of intensity

 

Neoplastic cells

Normal cells

Bcl2a

52.0–80.0

55.0

56.0–57.0

57.0

Bcl-xa

66.0–106.0

74.0

83.3–96.0

84.0

Bcl-xLa

109.5–156.0

136.9

80.7–95.0

83.0

Bcl-2 related protein A1a

78.5–128.0

93.8

74.7–87.0

79.2

BAG-1/RAP46a

69.0–102.0

77.0

68.0–76.0

74.6

Baka

90.0–142.0

114.5

88.5–101.3

98.5

Baxa

99.0–138.3

114.5

74.0–75.0

74.7

Bim/Boda

65.0–98.3

77.2

65.3–71.5

66.5

BIM-Longa

81.0–130.0

101.5

81.0–85.5

82.9

Bad (N-term)a

70.0–121.5

85.0

75.0–84.5

78.5

Bida

65.5–98.5

76.5

62.3–65.0

63.5

Pumaa

61.0–115.0

80.5

97.5–117.0

113.8

APAF1

102.0–150.0

124.0

83.0–93.0

87.0

Caspase 2

58.0–83.2

63.4

58.0–66.0

63.0

Cleaved Caspase 3b

68.8–107.0

81.0

61.0–73.0

62.5

Caspase 6 (c-term)b

63.0–90.0

74.0

62.0–82.0

66.5

Caspase 7b

69.5–107.5

80.3

65.0–72.0

66.0

Caspase 8b

85.0–151.0

115.4

78.0–115.0

82.0

Caspase 9p10b

90.5–138.0

107.0

55.0–68.0

59.0

Caspase 10 prob

67.0–91.5

77.0

60.0–70.0

61.0

Smac/Diablo

72.0–135.8

90.0

71,0–83.0

74.0

Cytochrome c

63.0–87.0

73.0

63.0–71.0

70.5

Survivin

66.0–97.0

80.1

73.0–85.0

80.5

  1. aImmunohistochemical data described in Coutinho-Camillo et al. [15]
  2. bImmunohistochemical data described in Coutinho-Camillo et al. [16]