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Table 3 Results of immunostaining quantitatively analyzed using an automated imaging system (ACIS III)

From: Profile of apoptotic proteins in oral squamous cell carcinoma: A cluster analysis of 171 cases

Protein Intensity (range) Median value of intensity Intensity (range) Median value of intensity
  Neoplastic cells Normal cells
Bcl2a 52.0–80.0 55.0 56.0–57.0 57.0
Bcl-xa 66.0–106.0 74.0 83.3–96.0 84.0
Bcl-xLa 109.5–156.0 136.9 80.7–95.0 83.0
Bcl-2 related protein A1a 78.5–128.0 93.8 74.7–87.0 79.2
BAG-1/RAP46a 69.0–102.0 77.0 68.0–76.0 74.6
Baka 90.0–142.0 114.5 88.5–101.3 98.5
Baxa 99.0–138.3 114.5 74.0–75.0 74.7
Bim/Boda 65.0–98.3 77.2 65.3–71.5 66.5
BIM-Longa 81.0–130.0 101.5 81.0–85.5 82.9
Bad (N-term)a 70.0–121.5 85.0 75.0–84.5 78.5
Bida 65.5–98.5 76.5 62.3–65.0 63.5
Pumaa 61.0–115.0 80.5 97.5–117.0 113.8
APAF1 102.0–150.0 124.0 83.0–93.0 87.0
Caspase 2 58.0–83.2 63.4 58.0–66.0 63.0
Cleaved Caspase 3b 68.8–107.0 81.0 61.0–73.0 62.5
Caspase 6 (c-term)b 63.0–90.0 74.0 62.0–82.0 66.5
Caspase 7b 69.5–107.5 80.3 65.0–72.0 66.0
Caspase 8b 85.0–151.0 115.4 78.0–115.0 82.0
Caspase 9p10b 90.5–138.0 107.0 55.0–68.0 59.0
Caspase 10 prob 67.0–91.5 77.0 60.0–70.0 61.0
Smac/Diablo 72.0–135.8 90.0 71,0–83.0 74.0
Cytochrome c 63.0–87.0 73.0 63.0–71.0 70.5
Survivin 66.0–97.0 80.1 73.0–85.0 80.5
  1. aImmunohistochemical data described in Coutinho-Camillo et al. [15]
  2. bImmunohistochemical data described in Coutinho-Camillo et al. [16]
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