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Table 2 Relative gene expression of BCL2 and p53 of CLL patients (treated only) according to different treatment regimens, data expressed as Mean ± SEM

From: Quantitative real time PCR analysis of apoptotic gene expression in chronic lymphocytic leukemia patients and their relationships with chemosensitivity

Treatment Regimen No. of Patients BCL2 expression P value P53 expression P value
Clb 5 1.7 ± 0.93 .338 0.12 ± 0.05 0.647
Clb + P 10 4.2 ± 1.42 .542 0.12 ± 0.05 0.583
Clb + (Clb + P) 6 7.5 ± 4.16 .972 0.45 ± 0.27 0.162
FCR 11 11.5 ± 4.89 .402 0.20 ± 0.06 0.977
FCR+ Clb + (Clb + P) 5 4.1 ± 1.85 .592 0.08 ± 0.04 0.50
FCR + (Clb + P) 4 1.6 ± 0.71 .371 0.23 ± 0.17 0.903
  1. Clb chlorambucil, P prednisolone, FCR: F fludarabine, C cyclophosphamide, R rituximab