Skip to main content

Table 3 Relative BCL2 and p53 gene expression in CLL patients (treated and untreated) according to disease duration from diagnosis date, data expressed as Mean ± SEM

From: Quantitative real time PCR analysis of apoptotic gene expression in chronic lymphocytic leukemia patients and their relationships with chemosensitivity

Duration of disease No. of Patient BCL2 expression P value P53 expression P value
ND 3 19.3 ± 14.0 0.054 0.16 ± 0.15 0.80
6 months 10 5.2 ± 2.29 0.418 0.11 ± 0.05 0.983
7-12 months 6 1.3 ± 0.69 0.718 0.15 ± 0.12 0.995
18 months 9 6.7 ± 2.66 0.532 0.16 ± 0.06 0.789
19–24 months 7 2.3 ± 0.86 0.656 0.10 ± 0.04 0.143
24–30 months 7 7.2 ± 3.56 0.559 0.45 ± 0.23 0.781
31–36 months 7 7.8 ± 4.74 0.864 0.21 ± 0.05 0.896
>36 months 6 6.0 ± 3.15 0.573 0.18 ± 0.10 0.763