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Table 3 Relative BCL2 and p53 gene expression in CLL patients (treated and untreated) according to disease duration from diagnosis date, data expressed as Mean ± SEM

From: Quantitative real time PCR analysis of apoptotic gene expression in chronic lymphocytic leukemia patients and their relationships with chemosensitivity

Duration of disease

No. of Patient

BCL2 expression

P value

P53 expression

P value

ND

3

19.3 ± 14.0

0.054

0.16 ± 0.15

0.80

6 months

10

5.2 ± 2.29

0.418

0.11 ± 0.05

0.983

7-12 months

6

1.3 ± 0.69

0.718

0.15 ± 0.12

0.995

18 months

9

6.7 ± 2.66

0.532

0.16 ± 0.06

0.789

19–24 months

7

2.3 ± 0.86

0.656

0.10 ± 0.04

0.143

24–30 months

7

7.2 ± 3.56

0.559

0.45 ± 0.23

0.781

31–36 months

7

7.8 ± 4.74

0.864

0.21 ± 0.05

0.896

>36 months

6

6.0 ± 3.15

0.573

0.18 ± 0.10

0.763