Fig. 1

Applications of iPSCs in cancer therapy. Induced pluripotent stem cells derived from cancer cells can be differentiate into T cells, DC and NK cells which on adoptive transfer into patient launch an attack on tumor; these iPSCs can also be exploited to understand the epigenetic reprogramming of cancer cells which could be used both as a therapy for cancer and as model to study cancer pathogenesis including drug screening. Additionally, gene editing technology could also be used to correct cancer mutation in iPSCs which could be differentiate into any cell types and could be used for further transplantation purpose