Skip to main content

Table 2 Discriminant formulaea

From: Molecular binary classification of NSCLC: miR-375 is a potential biomarker to differentiate SQCC from ADCC in Indian NSCLC patients

Sr.No. miRNA Discriminant function
1. miR-205, miR-21 Z1 = 2.233 – (0.132 x bNCtmiR-205) + (0.261 x NCtmiR-205)
2. miR-196b, miR-21 Z2 = 1.987 – (0.073 x NCtmiR-196b) + (0.191 x NCtmiR-21)
3. miR-375, miR-21 Z3 = (−0.637) + (0.439 x NCtmiR-375) + (− 0.245 x NCtmiR-21)
4. miR-205, miR-196b, miR-21 Z4 = 2.149 – (0.108 x NCtmiR-205) – (0.041 x NCtmiR-196b) + (0.191 x NCtmiR-21)
5. miR-205, miR-375, miR-21 Z5 = (−0.495) – (0.03 x NCtmiR-205) + (0.432 x NCtmiR-375) -(0.216 x NCtmiR-21)
6. miR-375, miR-196b, miR-21 Z6 = (−0.5982) + (0.438 x NCtmiR-375) – (0.034 x NCtmiR-196b) – (0.234 x NCtmiR-21)
7. miR-205, miR-196b, miR-375, miR-21 Z7 = (−0.514) – (0.016 x NCtmiR-205) – (0.03 x NCtmiR-196b) + (0.434 x NCtmiR-375) + (0.22 x NCtmiR-21)
  1. aDiscriminant formulae were developed with the help of IBM SPSS software
  2. b NCt normalised Ct (CtmiR – CtU6snRNA)