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Table 6 PPVa, NPVb AND DORc of miR-375 and miR-21 by ROC and DFA

From: Molecular binary classification of NSCLC: miR-375 is a potential biomarker to differentiate SQCC from ADCC in Indian NSCLC patients

  Variables ROC 95% CI DFA 95% CI
Training set PPV 87.5% 61.65% - 98.45% 87.5% 61.65% - 98.45%
NPV 92.86% 66.13% - 99.82% 92.86% 66.13% - 99.82%
DOR 91 7.3 - 1126.9 91 7.3 - 1126.9
Validation set PPV 93.75% 79.19% - 99.23% 93.75% 79.19% - 99.23%
NPV 96.43% 81.65% - 99.91% 96.43% 81.65% - 99.91%
DOR 405 34.73 - 4722.3 405 34.73 - 4722.3
  1. a PPV positive predictive value, PPV (True positive / True positive + False positive). b NPV negative predictive value, NPV (True negative / True negative + False negative). c DOR diagnostic odds ratio, Diagnostic Odds Ratio [(True positive / False positive) / (False negative / True negative)]
  2. Bold data signify DOR>1 which is the indication of better test performance