Molecular binary classification of NSCLC: miR-375 is a potential biomarker to differentiate SQCC from ADCC in Indian NSCLC patients

Table 6 PPV^a, NPV^b AND DOR^c of miR-375 and miR-21 by ROC and DFA

	Variables	ROC	95% CI	DFA	95% CI
Training set	PPV	87.5%	61.65% - 98.45%	87.5%	61.65% - 98.45%
	NPV	92.86%	66.13% - 99.82%	92.86%	66.13% - 99.82%
	DOR	91	7.3 - 1126.9	91	7.3 - 1126.9
Validation set	PPV	93.75%	79.19% - 99.23%	93.75%	79.19% - 99.23%
	NPV	96.43%	81.65% - 99.91%	96.43%	81.65% - 99.91%
	DOR	405	34.73 - 4722.3	405	34.73 - 4722.3

^a PPV positive predictive value, PPV (True positive / True positive + False positive). ^b NPV negative predictive value, NPV (True negative / True negative + False negative). ^c DOR diagnostic odds ratio, Diagnostic Odds Ratio [(True positive / False positive) / (False negative / True negative)]
Bold data signify DOR>1 which is the indication of better test performance