Skip to main content

Table 6 SNPs observed in constitutively spliced KLK7 mRNAs expressed in breast cancer tissues

From: Down regulation of KLK7 expression in breast tissues and identification of a novel spliced KLK7 mRNA

Sr. no. mRNA Polymorphism Position Effect on sequence of encoded protein Effect on 3D structure
1 SER2 1C+ after 1540 16–241 amino acids align with the reference protein Hydrolase, mannan-lectin serine protease1
A: C 6321
1C+ after 6321
G: A 6326
2 SER3 1C+ after 1540 16–241 amino acids align with the reference protein Hydrolase, mannan-lectin serine protease1
A: C 6321
1G+ after 6326
3 SER5 TGCTCAGTG: CCCTTAAAA 2047–2055 65–253 amino acids align with the reference protein Hydrolase, plasminogen
GAGCGCT: CCTTTTCA 2091–2097