Table 3 miRNAs expression levels in sera and tissues of CRC patients and normal control subjects
miRNAs assessed | CRC tissue (n = 124) (%) | Statistics | CRC serum (n = 41) (%) | Statistics |
|---|---|---|---|---|
miRNA-498 | χ2 = 12.4 | χ2 = 12.5 | ||
Normal | 74 (59.7) | P < 0.001 | 23(56.1) | P < 0.001 |
Over-expressed | 50 (40.3) | 18 (43.9) | ||
miRNA-21 | χ2 = 16.6 | χ2 = 13.5 | ||
Normal | 64 (51.6) | P < 0.001 | 22 (53.7) | P < 0.001 |
Over-expressed | 60 (48.4) | 19 (46.3) | ||
miRNA −145 | χ2 = 16.6 | χ2 = 13.5 | ||
Normal | 64 (51.6) | P < 0.001 | 22 (53.7) | P < 0.001 |
Down-expressed | 60 (48.4) | 19 (46.3) | ||
miRNA −137 | χ2 = 11.9 | χ2 = 13.5 | ||
Normal | 75 (60.5) | P < 0.001 | 22 (53.7) | P < 0.001 |
Down-expressed | 49 (39.5) | 19 (46.3) | ||
miRNA −320 | χ2 = 19.1 | χ2 = 15.6 | ||
Normal | 59 (47.6) | P < 0.001 | 20 (48.8) | P < 0.001 |
Down-expressed | 65 (52.4) | 21 (51.2) |