Table 7 The associations between the relevant clinic-pathological features of stage II CRC patients and disease free survival
Factors | N = 124 (%) | Disease free survival % | Median months (95% CI) | Log rankP value | ||||
|---|---|---|---|---|---|---|---|---|
1 yr | 2 yrs | 3 yrs | 5 yrs | 10 yrs | ||||
All | 124 (100) | 81.2 | 67.4 | 62.1 | 60.2 | 45.6 | 72.0 | NA |
Age (yrs) | ||||||||
≤ 45 | 60 (48.4) | 81.3 | 69.4 | 64.2 | 64.2 | 40.1 | 66 (52-79) | 0.917 |
> 45 | 64 (51.6) | 81.1 | 65.4 | 60.3 | 55.4 | 47.7 | 103 | |
Gender | ||||||||
Male | 64 (51.6) | 76.2 | 63.0 | 60.3 | 60.3 | 41.4 | 72 (4-139) | 0.41 |
Female | 60 (48.4) | 86.4 | 72.1 | 63.8 | 59.3 | 51.9 | NA | |
Residence | ||||||||
Urban | 66 (53.2) | 86.0 | 71.3 | 64.5 | 64.5 | 54.5 | NA | 0.225 |
Rural | 58 (48.4) | 81.0 | 63.0 | 59.9 | 55.3 | NA | 62 (21-102) | |
DM | ||||||||
- ve | 109 (87.9) | 81.3 | 67.5 | 64.4 | 62.3 | 47.2 | 103 | 0.414 |
+ ve | 15 (12.1) | 80.0 | 66.7 | 44.4 | NA | NA | 30 (21-38) | |
HTN | ||||||||
- ve | 110 (88.7) | 81.7 | 67.1 | 61.1 | 58.9 | 41.9 | 72 (14.8-129.1) | 0.434 |
+ ve | 14 (11.3) | 76.9 | 69.2 | 69.2 | 69.2 | 69.2 | NA | |
Family history | ||||||||
- ve | 103 (83.1) | 79.2 | 65.9 | 61.3 | 59.0 | 44.6 | 103 (28.2-177.5) | 0.804 |
+ ve | 21 (16.9) | 90.5 | 73.5 | 65.3 | 65.3 | 49.0 | NA | |
Smoking | ||||||||
- ve | 88 (71) | 94.4 | 75.6 | 73.4 | 70.2 | 53.0 | NA | 0.078 |
+ ve | 36 (29) | 74.3 | 57.0 | 52.6 | 52.6 | 39.5 | 103 (0-225) | |
PS | ||||||||
0 | 56 (45.2) | 89.3 | 81.7 | 79.2 | 75.5 | 51.0 | NA | 0.016 |
I | 48 (38.7) | 76.6 | 56.6 | 49.0 | 49.0 | 49.0 | 32 | |
II | 20 (16.1) | 68.6 | 52.3 | 43.5 | 43.5 | NA | 30 (8.1-51.9) | |
Pathology | ||||||||
Adenocarcinoma | 105 (84.7) | 82.5 | 68.5 | 62.3 | 60.2 | 47.5 | 72 | 0.713 |
Mucinous | 19 (15.3) | 73.7 | 61.4 | 61.4 | 61.4 | 40.6 | 103 (0-249) | |
Grade | ||||||||
I-II | 109 (87.9) | 81.3 | 68.7 | 64.2 | 62.1 | 46.4 | 102 | 0.425 |
III | 15 (12.1) | 80.0 | 58.7 | 46.9 | 46.9 | NA | 32 | |
T. stage | ||||||||
T3 | 84 (67.7) | 85.4 | 76.7 | 69.5 | 66.8 | 45.9 | 103 | 0.058 |
T4 | 40 (32.3) | 75.0 | 46.0 | 46.0 | 46.0 | 46.0 | 21 | |
Dissected LN | ||||||||
< 12 | 60 (48.4) | 81.7 | 69.5 | 64.5 | 60.9 | 44.3 | 66 (49.7-82.2) | 0.89 |
≥ 12 | 64 (51.6) | 80.7 | 65.4 | 60.2 | 60.2 | 48.1 | 103 | |
Adjuvant | ||||||||
No | 30 (24.2) | 88.6 | 70.8 | 61.0 | 54.2 | 54.2 | NA | 0.787 |
Yes | 94 (75.8) | 79.4 | 66.4 | 61.1 | 61.1 | 43.4 | 72 (25.3-118.7) | |