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Table 8 The correlation between clinico-pathological features of the patients and disease free survival

From: Aberrant expression of miRNAs predicts recurrence and survival in stage-II colorectal cancer patients from Egypt

Factors N = 124 (%) Disease free survival % Median months (95% CI) Log rank
P value
1 yr 2 yrs 3 yrs 5 yrs 10 yrs
All 124 (100) 91.0 76.1 72.4 69.1 56.5 NA NA
Age (yrs)
 ≤ 48 65 (52.4) 93.8 78.1 75.9 75.9 56.9 NA 0.412
 > 48 59 (47.6) 88.0 73.9 68.8 63.0 56.7 NA
Gender
 Male 64 (51.6) 88.9 73.8 70.0 70.0 55.7 NA 0.593
 Female 60 (48.4) 93.2 78.7 75.3 67.7 58.1 NA
Residence
 Urban 66 (53.2) 92.2 79.1 72.3 72.3 67.1 NA 0.343
 Rural 58 (48.4) 89.7 72.9 73.9 58.3 NA 75 (39.7-110.2)
DM
 - ve 109 (87.9) 91.6 76.6 74.2 70.8 57.9 NA 0.486
 + ve 15 (12.1) 86.7 72.7 54.4 NA NA NA
HTN
 - ve 110 (88.7) 89.9 77.0 72.7 68.9 54.3 NA 0.99
 + ve 14 (11.3) 100 69.2 69.2 69.2 69.2 NA
Family history
 - ve 103 (83.1) 89.1 74.5 72.0 68.0 56.8 NA 0.508
 + ve 21 (16.9) 100 83.2 71.3 71.3 53.3 NA
Smoking
 - ve 88 (71) 94.4 78.9 78.9 74.5 54.2 NA 0.741
 + ve 36 (29) 88.6 73.7 70.5 70.5 70.5 NA
PS
 0 56 (45.2) 94.6 86.6 86.6 81.0 66.0 NA 0.005
 I 48 (38.7) 89.4 68.9 65.9 65.9 52.7 NA
 II 20 (16.1) 84.4 62.2 40.8 40.8 NA 34 (16.2-51.8)
Pathology
 Adenocarcinoma 105 (84.7) 90.3 73.8 70.6 66.9 51.9 NA 0.205
 Mucinous adenocarcinoma 19 (15.3) 94.7 89.5 82.6 82.6 82.6 NA
Grade
 I-II 109 (87.9) 90.7 76.0 72.9 69.4 56.3 NA 0.919
 III-IV 15 (12.1) 93.3 76.0 67.9 67.9 NA NA
T.stage
 T3 84 (67.7) 92.7 83.3 80.1 75.3 56.9 NA NA
 T4 32 (25.8) 87.5 55.9 51.6 51.6 51.6 NA
 Missed 8 (6.4)       
Dissected LN
 < 12 60 (48.4) 90.0 79.3 73.6 67.9 51.4 NA 0.79
 ≥ 12 64 (51.6) 92.0 73.1 70.9 70.9 62.0 NA
Adjuvant
 No 30 (24.2) 91.4 82.8 79.3 63.4 47.6 75.0 0.697
 Yes 94 (75.8) 91.3 74.7 71.0 71.0 60.4 NA
Toxicity
 No 70 (56.5) 88.4 77.8 70.0 56.0 42.0 75.0 (32.9-117.2) 0.386
 Yes 54 (43.5) 94.4 74.3 74.3 74.3 63.2 NA
  1. The data in boldface denotes the presence of statistically significant difference between the studied groups