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Table 8 The correlation between clinico-pathological features of the patients and disease free survival

From: Aberrant expression of miRNAs predicts recurrence and survival in stage-II colorectal cancer patients from Egypt

Factors

N = 124 (%)

Disease free survival %

Median months (95% CI)

Log rank

P value

1 yr

2 yrs

3 yrs

5 yrs

10 yrs

All

124 (100)

91.0

76.1

72.4

69.1

56.5

NA

NA

Age (yrs)

 ≤ 48

65 (52.4)

93.8

78.1

75.9

75.9

56.9

NA

0.412

 > 48

59 (47.6)

88.0

73.9

68.8

63.0

56.7

NA

Gender

 Male

64 (51.6)

88.9

73.8

70.0

70.0

55.7

NA

0.593

 Female

60 (48.4)

93.2

78.7

75.3

67.7

58.1

NA

Residence

 Urban

66 (53.2)

92.2

79.1

72.3

72.3

67.1

NA

0.343

 Rural

58 (48.4)

89.7

72.9

73.9

58.3

NA

75 (39.7-110.2)

DM

 - ve

109 (87.9)

91.6

76.6

74.2

70.8

57.9

NA

0.486

 + ve

15 (12.1)

86.7

72.7

54.4

NA

NA

NA

HTN

 - ve

110 (88.7)

89.9

77.0

72.7

68.9

54.3

NA

0.99

 + ve

14 (11.3)

100

69.2

69.2

69.2

69.2

NA

Family history

 - ve

103 (83.1)

89.1

74.5

72.0

68.0

56.8

NA

0.508

 + ve

21 (16.9)

100

83.2

71.3

71.3

53.3

NA

Smoking

 - ve

88 (71)

94.4

78.9

78.9

74.5

54.2

NA

0.741

 + ve

36 (29)

88.6

73.7

70.5

70.5

70.5

NA

PS

 0

56 (45.2)

94.6

86.6

86.6

81.0

66.0

NA

0.005

 I

48 (38.7)

89.4

68.9

65.9

65.9

52.7

NA

 II

20 (16.1)

84.4

62.2

40.8

40.8

NA

34 (16.2-51.8)

Pathology

 Adenocarcinoma

105 (84.7)

90.3

73.8

70.6

66.9

51.9

NA

0.205

 Mucinous adenocarcinoma

19 (15.3)

94.7

89.5

82.6

82.6

82.6

NA

Grade

 I-II

109 (87.9)

90.7

76.0

72.9

69.4

56.3

NA

0.919

 III-IV

15 (12.1)

93.3

76.0

67.9

67.9

NA

NA

T.stage

 T3

84 (67.7)

92.7

83.3

80.1

75.3

56.9

NA

NA

 T4

32 (25.8)

87.5

55.9

51.6

51.6

51.6

NA

 Missed

8 (6.4)

      

Dissected LN

 < 12

60 (48.4)

90.0

79.3

73.6

67.9

51.4

NA

0.79

 ≥ 12

64 (51.6)

92.0

73.1

70.9

70.9

62.0

NA

Adjuvant

 No

30 (24.2)

91.4

82.8

79.3

63.4

47.6

75.0

0.697

 Yes

94 (75.8)

91.3

74.7

71.0

71.0

60.4

NA

Toxicity

 No

70 (56.5)

88.4

77.8

70.0

56.0

42.0

75.0 (32.9-117.2)

0.386

 Yes

54 (43.5)

94.4

74.3

74.3

74.3

63.2

NA

  1. The data in boldface denotes the presence of statistically significant difference between the studied groups