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Table 3 Expression of the proteins studied by immunohistochemistry and association with tumor site of oral carcinomas

From: Prognostic implications of the phosphatidylinositol 3-kinase/Akt signaling pathway in oral squamous cell carcinoma: overexpression of p-mTOR indicates an adverse prognosis

Variable Category TUMOR SITE Total
N° (%)
P value
Gingival
N° (%)
Hard Palate
N° (%)
Alveolar ridge
N° (%)
PI3K Negative 2 (6.7) 2 (6.9) 5 (8.3) 9 (7.6) 0.949
Positive 28 (93.3) 27 (93.1) 55 (91.7) 110 (92.4)
p-mTOR cytoplasm Negative 2 (6.7) 5 (16.7) 7 (11.9) 14 (11.8) 0.485
Positive 28 (93.3) 25 (83.3) 52 (88.1) 105 (88.2)
p-mTOR membrane Negative 15 (50.0) 22 (73.3) 29 (49.2) 66 (55.5) 0.075
Positive 15 (50.0) 8 (26.7) 30 (50.8) 53 (44.5)
p-mTOR nuclei Negative 17 (56.7) 13 (43.3) 38 (64.4) 68 (57.1) 0.164
Positive 13 (43.3) 17 (56.7) 21 (35.6) 51 (42.9)
p-AKT cytoplasm Negative 2 (6.7) 0 (0.0) 5 (8.3) 7 (5.8) 0.275
Positive 28 (93.3) 30 (100.0) 55 (91.7) 113 (94.2)
p-AKT nuclei Negative 12 (40.0) 10 (33.3) 21 (35.0) 43 (35.8) 0.850
Positive 18 (60.0) 20 (66.7) 39 (65.0) 77 (64.2)
p-MAPK cytoplasm Negative 2 (6.7) 3 (10.0) 9 (15.0) 14 (11.7) 0.483
Positive 28 (93.3) 27 (90.0) 51 (85.0) 106 (88.3)
p-MAPK nuclei Negative 11 (36.7) 15 (50.0) 24 (40.0) 50 (41.7) 0.539
Positive 19 (63.3) 15 (50.0) 36 (60.0) 70 (58.3)
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