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Table 4 Univariate analysis of disease-free survival rate according to clinicopathological findings and proteins expressions

From: Prognostic implications of the phosphatidylinositol 3-kinase/Akt signaling pathway in oral squamous cell carcinoma: overexpression of p-mTOR indicates an adverse prognosis

   Probability of accumulated disease-free survival  
Variable Category 1 year 3 year 5 years p* (log rank)
   (%) (%) (%)  
Gender Male 72.2 54.8 54.8 0.736
Female 72.2 60.8 55.3
Age 30–59 years 71.9 53.4 53.4 0.910
60–69 years 76.8 58.5 58.5
70–91 years 67.4 61.7 49.4
Tumor histological grade SCC I 82.0 63.2 60.6 0.001
SCC II e III 39.0 3.2 34.2
Clinical Stage I + II 70.4 70.4 70.4 0.457
III + IV 72.5 53.6 51.0
PI3K Negative 83.3 83.3 83.3 0.157
Positive 70.1 56.0 53.7
p-mTOR cytoplasm Negative 77.4 58.0 58.0 0.893
Positive 70.5 57.4 54.9
p-mTOR membrane Negative 75.2 55.5 51.5 0.745
Positive 67.3 60.7 60.7
p-mTOR nuclei Negative 68.5 50.1 47.0 0.037
Positive 75.0 70.3 70.3
p-MAPK cytoplasm Negative 92.9 66.5 66.5 0.360
Positive 68.1 56.3 53.9
p-MAPK nuclei Negative 73.6 60.6 53.9 0.837
Positive 70.7 55.8 55.8
p-AKT cytoplasm Negative 85.7 68.6 68.6 0.568
Positive 70.6 56.7 54.5
p-AKT nuclei Negative 67.9 59.9 59.9 0.923
Positive 74.4 56.8 53.8
PTEN cytoplasm Negative 84.9 74.3 66.0 0.152
Positive 66.6 51.0 51.0
PTEN nuclei Negative 84.4 70.3 62.5 0.228
Positive 66.6 51.0 51.0
TOTAL   72.3 57.0 54.9  
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