Table 1 Example Worksheet To Facilitate Adaptation Decisionsa
From: Successful adaptation of fever and neutropenia clinical practice guideline in China
Source Guideline Recommendation | Do not modify the initial empiric antibacterial regimen based solely on persistent fever in children who are clinically stable (Strong recommendation, Low quality evidence) |
Local Recommendation | After using cefepime for 7 days, change the dose to 1500 mg/m2/dose (MAX 2000 mg), IV every 12 h |
Concordance | No |
Required Supports | Ability to judge clinical stability |
Appropriate to Setting? If no, then stop | |
Facilitators and Barriers | |
Resources Required including Patient Costs | |
Other Comments |