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Table 3 Shows a comparison of the dosage used, the number of cycles and reported survival of landmark studies and this study

From: An alternative approach with a low dose and prolonged chemotherapy for palliative treatment of locally advanced, metastatic or recurrent squamous cell head and neck cancer

Drugs/cycles This study (Median dose) EXTREME regimen [7] TPEx regimen [11] TPF regimen [10] PCE regimen [14] SPECTRUM regimen [5]
Paclitaxel mg/m2 80     100  
Docetaxel mg/m2 32.5   75 75   
CISplatin mg/m2 45 100 75 75   100
CARBOplatin AUC 3 5    2.5  
5FU mg/m2/day 360 1000   750   1000
Cetuximab mg/m2 250 250 250   250  
Panitumumab mg/kg 3.5      9
Maximum cycles 14 (median 9) 6 4 4 6 6
PFS (months) 14.0 (CI: 5.3,22.6) 5.6 14 11 5.2 5.8
OS (months) 15.7 (CI: 1.7, 29.7) 10.1 6.2 18.8 14.7 11.1