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Table 2 Correlations between clinical and histopathological variables and VEGF or HIF1A expression

From: Prognostic value of factors associated with hypoxia and lipid metabolism in patients with colorectal cancer

Variable VEGF   HIF1A
Negative Positive Negative Positive  
Stage
 II CRC 8 (44.4) 40 (49.4)   13 (48.2) 35 (48.6)  
    0.705    0.967
 III CRC 10 (55.6) 41 (50.6)   14 (51.8) 37 (51.4)  
Histological grade
 Low grade 6 (33.3) 17 (21.2)   8 (29.6) 15 (21.1)  
    0.355a    0.375
 High grade 12 (66.7) 63 (78.8)   19 (70.4) 56 (78.9)  
Vascular invasion
 No 12 (66.7) 72 (88.9)   23 (85.2) 61 (84.7)  
    0.028 a    0.999a
 Yes 6 (33.3) 9 (11.1)   4 (14.8) 11 (15.3)  
Perineural invasion
 No 16 (88.9) 62 (76.5)   21 (77.8) 57 (79.2)  
    0.347a    0.880
 Yes 2 (11.1) 19 (23.5)   6 (22.2) 15 (20.8)  
Lymphatic invasion
 No 15 (83.3) 58 (71.6)   11 (40.7) 15 (20.8)  
    0.386a    0.045
 Yes 3 (16.7) 23 (28.4)   16 (59.3) 57 (79.2)  
  1. p-values calculated using the chi-square test
  2. a p-values calculated using Fisher’s exact test
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