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Table 2 Univariate and multivariate analyses of overall survival for patients with acute lymphoblastic leukemiaa

From: Increased levels of cyclin D1 negatively impacts on acute lymphoblastic leukemia overall survival

Factor Univariate analysis Multivariate analysis
HRb (95% C.I.) p HRb (95% C.I.) p
Age 1.04 1.02–1.07 < 0.001 1.04 1.02–1.08 < 0.001
BCR-ABL1 (positive vs. negative) 1.09 0.44–2.73 0.852 0.68 0.26–1.76 0.431
White blood cell count (× 109/L) 0.998 0.995–1.002 0.542 1.0007 0.997–1.004 0.702
Cyclin D1 expression 1.07 1.01–1.13 0.019 1.07 1.01–1.15 0.026
  1. Abbreviations: ALL, acute lymphoblastic leukemia; HR, hazard ratio; BCR-ABL1, breakpoint cluster region-abelson 1
  2. aPatients with ALL whose sample were collected at diagnosis (n = 40) were included in survival analysis
  3. bHazard ratios > 1 indicate that increasing values for continuous variable or the first factor for categorical variable has the poorer outcome
  4. Statistically significant p values are highlighted in bold