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Table 2 Univariate and multivariate analyses of overall survival for patients with acute lymphoblastic leukemiaa

From: Increased levels of cyclin D1 negatively impacts on acute lymphoblastic leukemia overall survival

Factor

Univariate analysis

Multivariate analysis

HRb

(95% C.I.)

p

HRb

(95% C.I.)

p

Age

1.04

1.02–1.07

< 0.001

1.04

1.02–1.08

< 0.001

BCR-ABL1 (positive vs. negative)

1.09

0.44–2.73

0.852

0.68

0.26–1.76

0.431

White blood cell count (× 109/L)

0.998

0.995–1.002

0.542

1.0007

0.997–1.004

0.702

Cyclin D1 expression

1.07

1.01–1.13

0.019

1.07

1.01–1.15

0.026

  1. Abbreviations: ALL, acute lymphoblastic leukemia; HR, hazard ratio; BCR-ABL1, breakpoint cluster region-abelson 1
  2. aPatients with ALL whose sample were collected at diagnosis (n = 40) were included in survival analysis
  3. bHazard ratios > 1 indicate that increasing values for continuous variable or the first factor for categorical variable has the poorer outcome
  4. Statistically significant p values are highlighted in bold
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Applied Cancer Research

ISSN: 1980-5578