Fig. 1

Type of alternative splicing event. a Alternative 5′ splice site. Two 5’ss are in competition for a single 3’ss. b Alternative 3′ splice site. Two 3’ss are in competition for a single 5’ss. c Cassette exon. An exon may be skipped. d Multiple exon skipping. A stretch of exons may be skipped together. e Mutually exclusive exon skipping. A choice between two alternative exons. f Alternative splicing event coupled to alternative polyadenylation g Alternative splicing event coupled to non-sense mediated decay. h Alternative transcription initiation