Applied Cancer Research

Table 1 Statistical analysis of ten whole sections stained for PTEN protein

From: PTEN loss in Gleason grade 7 prostate tumors exhibits intratumoral heterogeneity and is associated with unfavorable pathological features

	Homozygous	Hemizygous	Intact	P
Cell count	300,079	214,232	164,235	0.43
Area (μm²)	55,822,500	42,726,067	41,546,478	0.86
Average % + ve cells	57.87	90.20	85.63	0.01*
Average % -ve cells	42.13	9.80	14.38	0.01*

Average values are shown for each group. One-way ANOVA test was employed to determine the associations between PTEN copy number by FISH and PTEN protein loss by immunohistochemistry. *P < 0.05

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