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Fig. 4 | Applied Cancer Research

Fig. 4

From: Sequencing of RAS/RAF pathway genes in primary colorectal cancer and matched liver and lung metastases

Fig. 4

Lowest coverage per tissue type. a: primary tumor, b: liver metastasis, c: lung metastasis. Y-axis: the lowest coverage of samples in unique reads. Dotted line: the minimum absolute coverage of 125 unique reads x-axis: the percentage of samples. In all samples HRAS mutation analysis performs better (coverage above 125 unique reads in the highest percentage of samples), followed by BRAF, PIK3CA, and NRAS/KRAS. Sequencing of liver metastases more often result in enough coverage (75% of samples), followed by lung metastases (70% of samples) and primary tumors (60% of samples)

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Applied Cancer Research

ISSN: 1980-5578