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Table 1 Immunohistochemical expression of Chk2 and clinicopathological parameters evaluated in this study

From: Immunohistochemistry analysis of checkpoint kinase 2 in oral squamous cell carcinoma

Feature No (%) of patients (N = 101)
Chk2High expression58 (57.43%)
Low expression43 (42.57%)
SexMale88 (87.13%)
Female13 (12.87%)
Age< 4003 (2.97%)
41–6049 (48.5%)
> 6049 (48.51%)
SmokingYes81 (80.20%)
No18 (17.82%)
No information02 (1.98%)
Alcohol consumptionYes78 (77.23%)
No21 (20.79%)
No information02 (1.98%)
StagingECI04 (3.96%)
ECII11 (10.89%)
ECIII14 (13.86%)
ECIV33 (32.67%)
In situ01 (0.99%)
No information38 (37.62%)
Tumor sizeT105 (5.00%)
T221 (20.79%)
T311 (10.89%)
T426 (25.74%)
No information37 (36.63%)
In situ01 (0.99%)
Regional metastasisYes40 (39.60%)
No61 (60.40%)
Distant metastasisYes16 (15.84%)
No85 (84.16%)
Tumor histological gradeWell27 (26.73%)
Moderate63 (62.38%)
Poor10 (9.90%)
No information01 (0.99%)
RelapseYes43 (42.57%)
No56 (55.45%)
No information02 (1.98%)
DeathYes57 (56.44%)
No45 (43.56%)
  1. *Statistical significance determined as p ≤ 0.05