Fig. 7
Spheroids analysis. a Analysis of volumes (micrometers) of 3D cultures (spheroids) treated with PLN at concentrations of 0–40 μM before receiving the treatments (0 h) and after 24, 48 and 72 h. CPT: positive control using camptothecin 2.5 μM. b Micrographs (100 x) of the spheroids after 72 h of treatment