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Fig. 1 | Applied Cancer Research

Fig. 1

From: Biomarker testing for advanced lung cancer by next-generation sequencing; a valid method to achieve a comprehensive glimpse at mutational landscape

Fig. 1

OncoPrint showing the distribution of genomic alterations in 29 genes and 100 lung cancer cases. Note: For cases 1–30 the IonAmpliSeq™ Cancer Hotspot Panel V2 was used, and in cases 31–100 the Oncomine™ Solid Tumor DNA and Oncomine™ Solid Tumor Fusion Transcript kit was employed. Frequency (%) for the genes APC, ATM, FLT3, GNAQ, IDH2, JAK3, KDR, KIT, SMARCB1 and SMO have been calculated in 30 patients; and for fusion transcripts in ALK, RET and ROS1 has been calculated among the 70 tested cases. The frequency for all other genes, common to both the panels has been calculated in 100 cases. The red, green and blue asterisk symbol (*) indicates patients with ≥3, 2 and 1 pathogenic mutation(s), respectively. No mutation was detected in 14 cases

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