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Table 1 Relation of expression of P27KIP1 by Immunohistochemistry and RT-PCR and clinical and pathological data

From: Clinical significance of p27 Kip1 expression in advanced ovarian cancer

 IHCmRNA P27
P27 + veP27 -ve  Upregulation of P27Downregulation of P27  
N%N%t-testPN%N%t-testP
Stage
 IIIAa8802202.40.048802202.3720.042
 IIIBa1083.3216.73.090.011083.3216.73.0930.01
 IIICa2436.34263.72.320.022436.34263.72.3150.024
Grade
 Moderate + Well differentiated2686.7413.35.92<  0.0012686.7413.35.92<  0.001
 Poorly differentiated1627.64272.43.82<  0.0011627.64272.43.816<  0.001
Pathology
 Serous3861.32438.71.830.074062.52437.52.0660.043
 Non- serous415.42284.64.89< 0.00128.32291.77.405< 0.001
Ascites
 Absent2485.7414.35.92< 0.0012485.7414.35.396< 0.001
 Present183042703.380.001423.34676.74.892< 0.001
Response
 CR, Microscopic disease, PRa40876137.46< 0.0014189.1510.98.509< 0.001
 No response or progressive disease24.84095.213.7< 0.00113.44197.617.43< 0.001
Residual Disease
 >  2 cm183042703.380.00152545754.472< 0.001
 <  2 cm2485.7414.35.4< 0.00121757253.0550.005
  1. aCR Complete response, PR Partial response
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