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Fig. 3 | Applied Cancer Research

Fig. 3

From: Regulatory lymphocytes: the dice that resolve the tumor endgame

Fig. 3

Proposed mechanism of regulatory lymphocyte depletion therapy in the tumor. The model for depletion therapy suggests that by reducing Breg and Treg populations in the tumor microenvironment, B cells would be allowed to branch into plasmablast and plasma cells while T cells would differentiate into Th1 and Th17 cells. These differentiated B and T cells would, in turn, inhibit tumor cell growth and ultimately disrupt cancer progression

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