Fig. 3From: Regulatory lymphocytes: the dice that resolve the tumor endgameProposed mechanism of regulatory lymphocyte depletion therapy in the tumor. The model for depletion therapy suggests that by reducing Breg and Treg populations in the tumor microenvironment, B cells would be allowed to branch into plasmablast and plasma cells while T cells would differentiate into Th1 and Th17 cells. These differentiated B and T cells would, in turn, inhibit tumor cell growth and ultimately disrupt cancer progressionBack to article page