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  1. Review

    Genomics and epidemiology for gastric adenocarcinomas

    Whereas the pathological aspects of Gastric Adenocarcinomas (GACs) have been well defined, the actual knowledge of its genesis and evolution remains to be translated to better diagnosis and to more effective t...

    Applied Cancer Research 2017 37:7

    Published on: 10 March 2017

  2. Research Article

    A study on genetic polymorphism in Matrix Metalloproteinases-3 in oral submucous fibrosis patients and in healthy individuals

    OSF is a potentially malignant condition affecting the oral cavity and oropharynx. MMP-3 also known as Stromelysin -I is a key member of the MMP family which is responsible for degradation of collagen type II,...

    Preethi A. Poonja, Atul P. Sattur, Krishna N. Burde and Shivaprakash V. Hiremath

    Applied Cancer Research 2017 37:4

    Published on: 28 February 2017

  3. Research article

    The variable morphological spectrum of penile basaloid carcinomas: differential diagnosis, prognostic factors and outcome report in 27 cases classified as classic and mixed variants

    Basaloid carcinomas of the penis, HPV-related tumors, are morphologically less homogenous than originally thought. The study objective was to evaluate the prognostic influence of the basaloid pattern in mixed ...

    Isabel Alvarado-Cabrero, Diego Fernando Sanchez, Diana Piedras, Adriana Rodriguez-Gómez, Ingrid M. Rodriguez, Maria Jose Fernandez-Nestosa, Narciso Hernández-Toriz and Antonio L. Cubilla

    Applied Cancer Research 2017 37:3

    Published on: 22 February 2017

  4. Research article

    Profile of apoptotic proteins in oral squamous cell carcinoma: A cluster analysis of 171 cases

    Oral squamous cell carcinoma (OSCC) is the eighth most prevalent cancer worldwide. In recent large-scale studies, by immunohistochemistry and cluster analysis, several markers were associated with patient surv...

    Cláudia Malheiros Coutinho-Camillo, Silvia Vanessa Lourenço, Renato David Puga, Aline Santos Damascena, Tathyane Harumi Nakajima Teshima, Luiz Paulo Kowalski and Fernando Augusto Soares

    Applied Cancer Research 2017 37:2

    Published on: 24 January 2017

  5. Review

    Utilization of the oncoscan microarray assay in cancer diagnostics

    Current strategies for cancer patient management include the use of genomic and proteomic test results to help guide therapeutic selection. The need for multi-target variant analysis is highlighted by the grow...

    Hou-Sung Jung, Joel A. Lefferts and Gregory J. Tsongalis

    Applied Cancer Research 2017 37:1

    Published on: 10 January 2017

  6. Research article

    Diagnosis of micrometastasis in muscle invasive bladder cancer through immunohistochemistry analysis: is there indication for routine evaluation?

    Muscle invasive bladder cancer (BC) has a mortality rate of 50% in 5 years, despite the aggressive treatments currently used. The diagnosis of latent tumor cells in histologically normal lymph nodes (LN) may h...

    Gustavo Cuck, Isabela Werneck da Cunha, Walter Henriques da Costa, Clóvis Antônio Lopes Pinto, Carlos Alberto Ricetto Sacomani, Francisco Paulo da Fonseca and Gustavo Cardoso Guimarães

    Applied Cancer Research 2016 36:6

    Published on: 15 December 2016

  7. Review

    Vitamin D axis and its role in skin carcinogenesis: a comprehensive review

    Vitamin D (VD) is a secosteroid hormone that is mainly synthesized in the skin upon exposure to UVB radiation. VD is widely known for its role in calcium metabolism; however, multiple endocrine, paracrine and ...

    Constanza Del Puerto, Cristián Navarrete-Dechent, Montserrat Molgó, Arturo Borzutzky and Sergio González

    Applied Cancer Research 2016 36:5

    Published on: 8 December 2016

  8. Research article

    RUNX2 and WWOX genes as molecular biomarkers and candidates for targeted therapy in Egyptian patients with primary conventional osteosarcoma

    The conventional osteosarcoma (OS) is the commonest primary malignant, bone tumor with complex genomic profiles and poor survival. Runt-related transcription factor 2 (RUNX2) and WW domain containing oxidoreducta...

    Abeer A. Bahnassy, Eman Abdelzaher, Rania Gaber, Gamal Elhosseiny, Awad Abdel Moniem A. Rafalla, Abdel-rahman N. Zekri, Ahmad El-Bastawisi, Hend F. Yousif and Layla Kamal Younis

    Applied Cancer Research 2016 36:4

    Published on: 8 December 2016

  9. Review

    What is new in Genitourinary Pathology? Recent developments and highlights of the new 2016 World Health Organization classification of tumors of the urinary system and male genital organs

    The recently published 2016 World Health Organization (WHO) Classification of Tumors of the Urinary System and Male Genital Organs stems from the accumulated knowledge and data collected during the last 12 yea...

    Daniel Abensur Athanazio and Kiril Trpkov

    Applied Cancer Research 2016 36:1

    Published on: 24 November 2016

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