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Applied Cancer Research


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  1. Content type: Research article

    Circulating tumor cells (CTCs) play an important role in progression and metastasis, particularly in form of cluster, which is called circulating tumor microemboli (CTM), and can be found in the peripheral blo...

    Authors: Mônica Taiane de Macêdo Diaz, Emne Ali Abdallah, Milena Shizue Tariki, Alexcia Camila Braun, Aldo Lourenço Abbade Dettino, Ulisses Ribaldo Nicolau, Vanessa da Silva Alves and Ludmilla Thomé Domingos Chinen

    Citation: Applied Cancer Research 2018 38:8

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  2. Content type: Research article

    Cyclin D1 is a protein essential for transition from G1 to S phase during cell cycle progression, which has an oncogenic potential and is highly expressed in several human malignancies. However, in view of the he...

    Authors: Jaqueline Cristina Fernandes, Ana Paula Nunes Rodrigues Alves, Juan Luiz Coelho-Silva, Renata Scopim-Ribeiro, Bruna Alves Fenerich, Belinda Pinto Simões, Eduardo Magalhães Rego, João Agostinho Machado-Neto and Fabiola Traina

    Citation: Applied Cancer Research 2018 38:7

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  3. Content type: Research article

    Colorectal cancer (CRC) is the third most commonly diagnosed cancer worldwide. Brazil does not have an official well established program for screening colorectal cancer. The aim of this study was to compare Gu...

    Authors: Bruna Elisa Catin Kupper, Samuel Aguiar Junior, Wilson Toshihiko Nakagawa, Renata Mayumi Takahashi, Ranyell Matheus Spencer Sobreira Batista, Tiago Santoro Bezerra, Paulo Roberto Stevanato Filho, Thiago Celestino Chulam and Ademar Lopes

    Citation: Applied Cancer Research 2018 38:5

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  4. Content type: Research article

    Preoperative assessment of tumor size is important in breast cancer treatment planning, especially in breast conservation surgeries. The use of the Magnetic Resonance Imaging (MRI) is increasing among patients...

    Authors: Luciana Karla Lira França, Almir Galvão Vieira Bitencourt, Cynthia Aparecida Bueno de Toledo Osório, Luciana Graziano, Camila Souza Guatelli, Juliana Alves Souza and Elvira Ferreira Marques

    Citation: Applied Cancer Research 2018 38:2

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  5. Content type: Research article

    Data on renal replacement therapy (RRT) in cancer patients with acute kidney injury (AKI) in the intensive care unit (ICU) and how these factors influence the efficiency of dialysis and the outcomes of these p...

    Authors: Edwiges Ita de Miranda Moura, Germana Alves de Brito, Juliana Vendramini Cordeiro Fernandes, Lilian Guardian, Joubert Araujo Alves, Fabiana Plaza Sequeira, Marina Harume Imanishe and Benedito Jorge Pereira

    Citation: Applied Cancer Research 2018 38:3

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  6. Content type: Research article

    The creation and evolution of research nurse, connected with some specialty, brings a new path to be covered and structured inside nursering. The position of Researcher Nurse was initially created decentralize...

    Authors: Bruna Tirapelli, Silvana Soares dos Santos, Bruna Elisa Catin Kupper and Amanda Aparecida França de Nobrega

    Citation: Applied Cancer Research 2018 38:1

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  7. Content type: Review

    Follicular dendritic cell (FDC) tumor is an uncommon neoplasm. It generally presents as a slow-growing, painless mass, without systemic symptoms. Histological features usually include low grade spindle cell pr...

    Authors: Aline Caldart Tregnago, Diogo Lago Morbeck, Felipe D’Almeida Costa, Antonio Hugo José Froes M. Campos, Fernando Augusto Soares and José Vassallo

    Citation: Applied Cancer Research 2017 37:45

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  8. Content type: Research article

    Colorectal cancer (CRC) is a neoplasia with high incidence and mortality rates. It had been suggested that the inflammatory response is an important CRC prognostic factor. The disordered and accelerated prolif...

    Authors: Adriano Carneiro da Costa, Paulo Roberto Stevanato Filho, Samuel Aguiar Júnior, Fábio de Oliveira Ferreira, Maria Dirlei Begnami, Vladmir Cláudio Cordeiro de Lima, Fernando de Santa Cruz Oliveira, Wilson Toshihiko Nakagawa, Ranyell Matheus Spencer and Ademar Lopes

    Citation: Applied Cancer Research 2017 37:44

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  9. Content type: Research article

    It is expected that about 65,000 new patients will be diagnosed with head and neck cancer in 2017 in the United States. Patients with recurrent or advanced or metastatic head and neck do not have good survival...

    Authors: Rohit Bishnoi, Chintan Shah, Harini Bejjanki, Jeffery A. Bennett and David N. Reisman

    Citation: Applied Cancer Research 2017 37:43

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  10. Content type: Research article

    The development of oral cavity cancer is related to the accumulation of genetic alterations. The activation of AKT is associated with the proliferation and progression of many malignancies. It is thought that ...

    Authors: Darkle Modesto Ferreira, Tercia J. Neves, Luiz Guilherme C. A. Lima, Fabio A. Alves and Maria D. Begnami

    Citation: Applied Cancer Research 2017 37:41

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  11. Content type: Research article

    Functional speech rehabilitation after total laryngectomy remains one of the most challenging issues in head and neck multidisciplinary care. Tracheoesophageal puncture for voice prosthesis insertion performed...

    Authors: Adriane Graicer Pelosof, Alvaro Moura Seraphim, Claudia Zitron Sztokfisz, Jose Guilherme Vartanian and Luiz Paulo Kowalski

    Citation: Applied Cancer Research 2017 37:42

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  12. Content type: Research article

    Patients with stage II CRC have a varying survival outcome. Therefore, it is critical to identify prognostic biomarkers that can define more aggressive forms of the disease. We assessed the expression levels o...

    Authors: Abeer A. Bahnassy, Mohammad El-Sayed, Nasr M. Ali, Ola Khorshid, Marwa M. Hussein, Hend F. Yousef, Marwa A. Mohanad, Abdel-Rahman N. Zekri and Salem E. Salem

    Citation: Applied Cancer Research 2017 37:39

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  13. Content type: Research article

    Tet methylcytosine dioxygenase 2 (TET2) is frequently mutated and/or downregulated in myeloid neoplasm, including myelodysplastic syndromes. Despite the extensive studies, the specific contribution of TET2 in ...

    Authors: Renata Scopim-Ribeiro, João Agostinho Machado-Neto, Adriana da Silva Santos Duarte, Fernando Ferreira Costa, Sara Teresinha Olalla Saad and Fabiola Traina

    Citation: Applied Cancer Research 2017 37:38

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  14. Content type: Research article

    Alternative splicing commonly occurs in cancer cells and many cancer specific splice variants have been reported as potential candidate biomarkers of the disease. We have studied human tissue Kallikrein 7 (KLK...

    Authors: Samina Ejaz, Faiz-ul-Hassan Nasim, Muhammad Ashraf and Gulzar Ahmad

    Citation: Applied Cancer Research 2017 37:35

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  15. Content type: Research article

    Cutaneous melanoma (CM) is the most aggressive subtype of skin cancer, with increasing incidence over the past several decades. DNA methylation is a key element of several biological processes such as genomic ...

    Authors: Dimitrius T. Pramio, André Y. Kashiwabara, Paula C. Pennacchi, Maria P. Rivas, Silvya S. Maria-Engler, Antônio H. J. F. M. Campos, João P. Duprat, Dirce M. Carraro and Ana C. V. Krepischi

    Citation: Applied Cancer Research 2017 37:34

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  16. Content type: Research article

    Melanoma is a metastatic type of skin cancer that is difficult to treat and the majority of efforts are directed to the design of new drugs. Medicinal Plants have been the primary source of medicines since lif...

    Authors: Sonam Pandey

    Citation: Applied Cancer Research 2017 37:33

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  17. Content type: Research article

    Pancreatic cancer has a poor prognosis. Patients might be better able to cope with their disease when the information is discussed that they consider most important. We investigated what questions pancreatic p...

    Authors: Lisa J. M. Ronde-Schoone, Chulja J. Pek, Rutger-Jan Swijnenburg and Arwen H. Pieterse

    Citation: Applied Cancer Research 2017 37:32

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  18. Content type: Research article

    In recent decades neoadjuvant therapies such as combined chemotherapy and radiotherapy have been introduced for cancer management. Compared with monotherapy modalities, neoadjuvant therapy is associated with g...

    Authors: Ali Ebrahimi Fard, M. B. Tavakoli, Hossein Salehi and Hamid Emami

    Citation: Applied Cancer Research 2017 37:29

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  19. Content type: Research article

    MIP is a cultivable, non-pathogenic organism, which shares several antigens with Mycobacterium tuberculosis and Mycobacterium leprae. It has several proposed clinical applications. However, its cytotoxic effect o...

    Authors: A. Darji, N. Desai, R. Modi, B. Khamar and S. Rajkumar

    Citation: Applied Cancer Research 2017 37:30

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  20. Content type: Research article

    Current developments in the targeted therapies of non-small-cell lung carcinoma demand accurate classification to dodge the adverse drug response and to yield maximum therapeutic outcome. Accurate classificati...

    Authors: Sangeet Bhaumik, Firoz Ahmad and Bibhu Ranjan Das

    Citation: Applied Cancer Research 2017 37:28

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